The setting is lush Astraea Hill, where three famous all-girls schools are built. It's the first day of school, and the cherry blossoms are scattering to the ground. Nagisa meets Shizuma Hanazono, the top student in the school, and her breath is taken away by her beauty. But when Shizuma takes a liking to Nagisa, love and chaos soon follow... (Source: Seven Seas Entertainment)

The first two volumes of Strawberry Panic! were published in English by Seven Seas Entertainment from March 18, 2008, to July 8, 2008. An omnibus titled Strawberry Panic: The Complete Novel Collection, which contained all three volumes, was published on June 7, 2011.