The mixed twins—Kobayashi Mitsuru and Kobayashi Megumu, who haven't seriously fallen in love for someone and other who doesn't know anything more than 2D world. A situation arises were Megumu and Mitsuru are forced to cross dress, and go to school? Mitsuru's encounter with a cute girl in Megumu's school and Megumu's meeting with the guy she met earlier is actually in her brother's school?? Will they find themselves and their first love?? Included one-shot: Volume 15: Megami-sama wa Furimukanai!?

Kobayashi ga Kawai sugite Tsurai!! was published in English as So Cute It Hurts!! by VIZ Media under the Shojo Beat imprint from June 2, 2015 to October 8, 2017. The series has also been published by Shogakukan Asia as Koba Cute since May 28, 2014.