Chiyoko "Choco" Sakurai and Mimi Nekota are best friends with very different personalities. Choco is studious and hard-working while Mimi is a spoiled and imaginative free-spirit, yet both of them have the same flair for fashion and desire to look cute. Following them on their journey through junior high school are their friends, Ryunosuke "Andrew" Ando, Komei Mikami, Mumu Momoyama, and Kojika "Bambi" Mori. The six of them put their own unique spin on romance, school, and life in general. [Written by MAL Rewrite]

Chokomimi was partially published in English as Chocomimi by VIZ Media, who published the first five volumes from July 7, 2009 to November 2, 2010, under the VIZ Kids imprint, before the license was dropped. The series went on hiatus in the September 2019 issue of Ribon due to Sonoda's health. She later died from breast cancer on August 4, 2019, ending the series' publication in the same issue.