The adventures of the cute and energetic Niko Kanzaki in the semi-demonic prestigious school, St. Lunatic School. First having entered due to her brother getting a job there, Niko discovers the haunting secret of the school in her night-classes, which are overrun with demons! She learns differences between humans and demons, but the handsome and mysterious Ren shows her that their two races may share some things in common.

Yoru ni mo Makezu! was first published in English as St. Lunatic High School by Tokyopop from August 7 to December 11, 2007. VIZ Media later took over the license, and published the title digitally under the VIZ Select imprint from August 26 to September 30, 2014.